Thomas W Grunt Selected Research

4- ((3- bromophenyl)amino)- 6,7- dimethoxyquinazoline

11/2007	The DNA-binding epidermal growth factor-receptor inhibitor PD153035 and other DNA-intercalating cytotoxic drugs reactivate the expression of the retinoic acid receptor-beta tumor-suppressor gene in breast cancer cells.
4/2005	An EGF receptor inhibitor induces RAR-beta expression in breast and ovarian cancer cells.

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Thomas W Grunt Research Topics

Disease

16	Neoplasms (Cancer) 01/2021 - 01/2003
13	Ovarian Neoplasms (Ovarian Cancer) 01/2021 - 01/2003
6	Breast Neoplasms (Breast Cancer) 01/2017 - 05/2003
4	Neoplasm Metastasis (Metastasis) 01/2021 - 05/2003
4	Carcinoma (Carcinomatosis) 05/2018 - 04/2005
2	Colorectal Neoplasms (Colorectal Cancer) 01/2021 - 01/2015
1	Ascites 01/2021
1	Melanoma (Melanoma, Malignant) 01/2021
1	Prostatic Neoplasms (Prostate Cancer) 01/2021
1	Disease Progression 01/2021
1	Fibrosis (Cirrhosis) 01/2015
1	Idiopathic Pulmonary Fibrosis 01/2015
1	Colonic Neoplasms (Colon Cancer) 01/2015
1	Multiple Myeloma 09/2012

Drug/Important Bio-Agent (IBA)

5	Pharmaceutical PreparationsIBA 01/2021 - 09/2011
5	RetinoidsIBA 11/2007 - 01/2003
4	EnzymesIBA 01/2021 - 06/2010
4	Fatty Acid Synthases (Fatty Acid Synthase)IBA 02/2017 - 07/2009
4	ErbB Receptors (EGF Receptor)IBA 12/2011 - 04/2005
3	retinoic acid receptor betaIBA 11/2007 - 04/2005
2	1,3- bis((3,4,5- trihydroxybenzoyl)oxy)naphthaleneIBA 01/2021 - 10/2020
2	Proteins (Proteins, Gene)FDA Link 01/2021 - 12/2011
2	Cetuximab (Erbitux)FDA Link 12/2011 - 07/2009
2	CollagenIBA 12/2011 - 05/2003
2	Canertinib (CI 1033)IBA 09/2011 - 07/2009
2	EKB 569IBA 09/2011 - 07/2009
2	Protein Isoforms (Isoforms)IBA 06/2010 - 11/2007
2	4- ((3- bromophenyl)amino)- 6,7- dimethoxyquinazolineIBA 11/2007 - 04/2005
2	DNA (Deoxyribonucleic Acid)IBA 11/2007 - 04/2005
2	Tretinoin (Retinoic Acid)FDA LinkGeneric 04/2005 - 01/2003
1	dBET6IBA 01/2021
1	Immune Checkpoint ProteinsIBA 01/2021
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2021
1	Interferon-gamma (Interferon, gamma)IBA 01/2021
1	LipidsIBA 01/2021
1	LDL Lipoproteins (beta Lipoproteins)IBA 01/2021
1	IntegrinsIBA 01/2019
1	ponatinibIBA 05/2018
1	Annexin A5IBA 05/2018
1	Phosphotransferases (Kinase)IBA 05/2018
1	Caspase 3 (Caspase-3)IBA 05/2018
1	NitrogenIBA 05/2017
1	Zoledronic Acid (Zometa)FDA Link 01/2017
1	Estradiol (Delestrogen)FDA LinkGeneric 01/2017
1	Hormones (Hormone)IBA 01/2017
1	Antineoplastic Agents (Antineoplastics)IBA 01/2016
1	RNA IsoformsIBA 01/2015
1	Circular RNAIBA 01/2015
1	Dipeptidyl Peptidase 4 (Dipeptidyl Peptidase IV)IBA 01/2015
1	AC133 AntigenIBA 01/2015
1	Protein Kinases (Protein Kinase)IBA 02/2013
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 09/2012
1	Messenger RNA (mRNA)IBA 09/2012
1	AntigensIBA 09/2012
1	Tetracycline (Achromycin)FDA LinkGeneric 12/2011
1	Lapatinib (GW572016)FDA Link 12/2011
1	Mitogen-Activated Protein KinasesIBA 12/2011
1	dactolisibIBA 09/2011
1	Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA 09/2011
1	Biological ProductsIBA 07/2010
1	CASP8 and FADD-Like Apoptosis Regulating Protein (FLIP-S)IBA 06/2010
1	Protein CIBA 06/2010
1	matuzumabIBA 07/2009
1	Erlotinib Hydrochloride (CP 358,774)FDA Link 07/2009
1	Trastuzumab (Herceptin)FDA Link 07/2009
1	Isotretinoin (Accutane)FDA LinkGeneric 05/2003
1	Neuregulin-1 (Neuregulin 1)IBA 05/2003
1	Interferon-alpha (Interferon Alfa)IBA 05/2003
1	GelsIBA 05/2003
1	TyrphostinsIBA 01/2003
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2003
1	tyrphostin AG825IBA 01/2003
1	AG-879IBA 01/2003

Therapy/Procedure

3	Therapeutics 01/2021 - 04/2005
1	Molecular Targeted Therapy 02/2013